CCR2 antagonist 1


CAS No. : 1683534-96-4

1683534-96-4
Price and Availability of CAS No. : 1683534-96-4
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Cat. No. : HY-112792
M.Wt: 549.47
Formula: C28H32BrF3N2O
Purity: >98 %
Solubility: DMSO : 125 mg/mL (ultrasonic)
Introduction of 1683534-96-4 :

CCR2 antagonist 1 is a high-affinity and long-residence-time CCR2 antagonist, with a Ki of 2.4 nM. IC50 & Target: Ki: 2.4 nM (CCR2)[1]. In Vitro: The combination of SAR and SKR in the hit-to-lead process results in the discovery of a new higheaffinity and longeresidenceetime CCR2 antagonist (CCR2 antagonist 1 (compound 15a), Ki=2.4 nM; RT=714 min)[1].

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