Vofopitant (dihydrochloride)


CAS No. : 168266-51-1

(Synonyms: GR 205171A)

168266-51-1
Price and Availability of CAS No. : 168266-51-1
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5mg $300 In-stock
10mg $480 In-stock
50mg $1360 In-stock
100mg $1860 In-stock
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Cat. No. : HY-12143
M.Wt: 505.36
Formula: C21H25Cl2F3N6O
Purity: >98 %
Solubility: DMSO : 33.33 mg/mL (ultrasonic);H2O : 33.33 mg/mL (ultrasonic)
Introduction of 168266-51-1 :

Vofopitant dihydrochloride (GR 205171A) is a potent, selective and orally available tachykinin neurokinin 1(NK1) receptor antagonist, inhibits [3H]SP binding to the NK1 receptor with pKi values of 9.5 and 10.6 in rat and human membranes respectively, acts as a potential broad-spectrum anti-emetic agent[1]. IC50 & Target:pKi: 9.5 (NK1, rat), 10.6 (NK1, human)[1]

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