GNE-6468
CAS No. : 1677668-27-7
| Size | Price | Stock |
|---|---|---|
| 5mg | $380 | In-stock |
| 10mg | $620 | In-stock |
| 50mg | $1700 | In-stock |
| 100mg | $2550 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-19775 |
| M.Wt: | 433.84 |
| Formula: | C23H16ClN3O4 |
| Purity: | >98 % |
| Solubility: | DMSO : 5 mg/mL (ultrasonic) |
GNE-6468 is a highly potent and selective RORγ (RORc) inverse agonist with an EC50 value of 13 nM for HEK-293 cell. GNE-6468 exhibits an EC50 of 30 nM for IL-17 PBMC[1].
In Vivo: GNE-6468 (compound 28) displays high predicted clearance values in human and rodent hepatocytes (CLhep = 17 and 42 mL/min/kg, respectively) [1].
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