Ornidazole


CAS No. : 16773-42-5

(Synonyms: Ro 7-0207)

16773-42-5
Price and Availability of CAS No. : 16773-42-5
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10g $105 In-stock
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Cat. No. : HY-B0508
M.Wt: 219.63
Formula: C7H10ClN3O3
Purity: >98 %
Solubility: H2O : 10 mg/mL (ultrasonic);DMSO : ≥ 100 mg/mL
Introduction of 16773-42-5 :

Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease[1][2][3]. In Vitro:Ornidazole exhibits inhibitory activity against anaerobic bacteria, including Bacteroides fragilis, B. melaninogenicus, fusobacteria, clostridia, Lactobacillus, and Actinomyces[2].
Ornidazole (0-1200 μg/mL, 24-72 h) inhibits the viability of mouse melanoma cell B16F10, blocks the migration ability of B16F10 cell, and induces DNA damage[3].
In Vivo:Ornidazole (80 mg/kg, ip, once daily for 12 days) affects endoplasmic reticulum (ER) stress, exhibits antitumor efficacy in B16F10 xenograft mouse models[3].

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