Rodatristat
CAS No. : 1673568-73-4
(Synonyms: KAR5417)
| Size | Price | Stock |
|---|---|---|
| 5mg | $610 | In-stock |
| 10mg | $980 | In-stock |
| 50 mg | Get quote | |
| 100 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-120083 |
| M.Wt: | 561.98 |
| Formula: | C27H27ClF3N5O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 20 mg/mL (ultrasonic;warming;heat to 80°C) |
Rodatristat (KAR5417) is a potent tryptophan hydroxylase 1 (TPH1) and TPH2 inhibitor with IC50s value of 33 nM and 7 nM, respectively, and shows robust reduction of intestinal serotonin (5-HT) levels in mice[1]. IC50 & Target: IC50: 33 nM (TPH1) and 7 nM (TPH2)[1] In Vivo: Rodatristat (10-50 mg/kg; oral administration; mice) treatment decreases intestinal 5-HT concentrations at 50 mg/kg, their efficacy drop off significantly at the lower 10 mg/kg dose[1].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- Rodatristat
- Cat. No.:
- HY-120083
- Quantity:
Your information is safe with us.