SCH 51866
CAS No. : 167298-74-0
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| Cat. No. : | HY-116262 |
| M.Wt: | 389.37 |
| Formula: | C19H18F3N5O |
| Purity: | >98 % |
| Solubility: |
SCH 51866 is a potent, selective and orally active inhibitor of PDE1 (IC50=70 nM) and PDE5 (IC50=60 nM). SCH 51866 inhibits collagen-induced aggregation of human washed platelets (IC50=10 μM), prevents neointimal formation in balloon catheter-injured carotid arteries of spontaneously hypertensive rats (SHR), and reduces blood pressure in SHR. SCH 51866 can be used in the study of hypertension[1].
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