4-Hydroxyantipyrine


CAS No. : 1672-63-5

(Synonyms: 4-Hydroxyphenazone; NSC 174055)

1672-63-5
Price and Availability of CAS No. : 1672-63-5
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100mg $20 In-stock
250mg $22 In-stock
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5g $197 In-stock
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Cat. No. : HY-B2150
M.Wt: 204.23
Formula: C11H12N2O2
Purity: >98 %
Solubility: DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 1672-63-5 :

4-Hydroxyantipyrine (4-Hydroxyphenazone; NSC 174055) is the major metabolite of Antipyrine (HY-B0171), can be as a biodistribution promoter. 4-Hydroxyantipyrine can increase distribution of concentration ratio of Citicoline and Antipyrine in the brain[1][2]. In Vitro: 4-Hydroxyantipyrine increase the tissue-to-plasma concentration ratio of Citicoline in the brain and liver and that of thiopental sodium in the brain, liver, and heart[1].
4-Hydroxyantipyrine enhances the blood-brain barrier (BBB) permeability of Antipyrine considering to be concerned with the increase of the Kp value of Antipyrine in the brain[2].

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