Autocamtide-2-related inhibitory peptide
CAS No. : 167114-91-2
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| Cat. No. : | HY-P0214 |
| M.Wt: | 1497.74 |
| Formula: | C64H116N22O19 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM. IC50 & Target:IC50: 40 nM (CaMKII)[1]. In Vitro: It is found that Autocamtide-2-related inhibitory peptide (a novel synthetic peptide ATP) is a potent inhibitor of CaM-kinase II with an IC50 of 40 nM, which is active in the presence or absence of Ca2+/calmodulin. It is 50 and 500 times more potent than CaMK-(281-302Ala286) and KN-93,respectively, under the assay condition used[1].
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