L-162537


CAS No. : 167027-99-8

167027-99-8
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Cat. No. : HY-108120
M.Wt: 632.71
Formula: C38H32N8O2
Purity: >98 %
Solubility:
Introduction of 167027-99-8 :

L-162537 is a competitive human angiotensin II receptor 1 (AT1) and receptor 2 (AT2) antagonist with an IC50=1.7 nM for AT1. L-162537 inhibits Ang II-mediated vasoconstriction, blood pressure elevation and related pathological signaling pathways. L-162537 is promising for research of angiotensin II-related cardiovascular diseases such as hypertension[1].

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