GV-196771A
CAS No. : 166974-23-8
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| Cat. No. : | HY-19243 |
| M.Wt: | 423.22 |
| Formula: | C20H13Cl2N2NaO3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
GV-196771A is the sodium salt form of GV196771, is an NMDA receptor antagonist. IC50 & Target: NMDA receptor[1] In Vivo: GV196771 is a potent antagonist of the modulatory glycine site of the N-methyl-D-aspartate receptor. GV196771 is a potent antagonist of the modulatory glycine site of the NMDA receptor developed for treatment of neuropathic pain. GV196771 is an NMDA receptor antagonist with low oral bioavailability in rats and mice. GV196771 has low oral bioavailability (<10%) and plasma clearance (~2 mL/min/kg) in rats[1].
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