Metaxalone (Standard)


CAS No. : 1665-48-1

(Synonyms: AHR438 (Standard); NSC170959 (Standard))

1665-48-1
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Cat. No. : HY-B0678R
M.Wt: 221.25
Formula: C12H15NO3
Purity: >98 %
Solubility: DMSO : ≥ 100 mg/mL
Introduction of 1665-48-1 :

Metaxalone (Standard) is the analytical standard of Metaxalone. This product is intended for research and analytical applications. Metaxalone (AHR438; NSC170959) is an FDA-approved muscle relaxant. Metaxalone acts mainly on the central nervous system and achieves muscle relaxation by inhibiting polysynaptic reflex arcs. In addition, Metaxalone is an inhibitor of MAO-A, which has anti-inflammatory and antioxidant effects. Metaxalone inhibits IL-1β-induced inflammatory phenotype, modulates NF-κB and other related signaling pathways, and decreases MAO-A expression and activity in IL-1β-treated microglia[1][2].

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