PNU-103017
CAS No. : 166335-18-8
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| Cat. No. : | HY-19236 |
| M.Wt: | 504.60 |
| Formula: | C28H28N2O5S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
PNU-103017 is an HIV protease inhibitor. IC50 & Target: HIV protease[1] In Vivo: PNU-103017 is a selective HIV aspartyl protease inhibitor under evaluation as a potential oral treatment of Acquired Immunodeficiency Diseases. PNU-103017 is a racemic mixture of two enantiomers, designated PNU-103264 (R-) and PNU-103265 (S-). The Cmax (P≤0.0349), Cmin (P≤0.0168), and Cav (P≤0.0118) are significantly higher for the (R)- than the (S)-enantiomer, showing enantioselective pharmacokinetics of PNU-103017 in the dog[1].
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