MLS000532223
CAS No. : 16616-39-0
| Size | Price | Stock |
|---|---|---|
| 5mg | $340 | In-stock |
| 10mg | $540 | In-stock |
| 25mg | $920 | In-stock |
| 50mg | $1450 | In-stock |
| 100mg | $2180 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-117149 |
| M.Wt: | 251.24 |
| Formula: | C15H9NO3 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
MLS000532223 is a high affinity, selective inhibitor of Rho family GTPases, with EC50 values ranging from 16 μM to 120 μM. MLS000532223 prevents GTP binding to several GTPases[1].
IC50 & Target: EC50: 16-120 μM (Rho family GTPases)[1]
In Vitro: MLS000532223 prevents GTP binding to several GTPases in a dose-dependent manner[1].
MLS000532223 modulates Rho-family GTP-binding kinetics[1].
MLS000532223 is active in cell-based assays and inhibits EGF-stimulated Rac 1 activation[1].
MLS000532223 inhibits actin rearrangements and changes in cell morphology that are downstream of Rho family GTPase activation[1].
MLS000532223 (10 μM) modulates actin remodeling in mast cells[1].
MLS000532223 (10 μM) inhibits ligand-stimulated β-hexosaminidase secretion of RBL cells[1].
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