Fmoc-8-amino-3,6-dioxaoctanoic acid
CAS No. : 166108-71-0
(Synonyms: Fmoc-NH-PEG2-CH2COOH)
| Size | Price | Stock |
|---|---|---|
| 1g | $10 | In-stock |
| 5g | $17 | In-stock |
| 10g | $31 | In-stock |
| 25g | $65 | In-stock |
| 100g | $248 | In-stock |
| 500g | $1067 | In-stock |
| 1000g | $1848 | In-stock |
| > 2 kg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-W007713 |
| M.Wt: | 385.41 |
| Formula: | C21H23NO6 |
| Purity: | >98 % |
| Solubility: | DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C) |
Fmoc-8-amino-3,6-dioxaoctanoic acid (Fmoc-NH-PEG2-CH2COOH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-8-amino-3,6-dioxaoctanoic acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- Fmoc-8-amino-3,6-dioxaoctanoic acid
- Cat. No.:
- HY-W007713
- Quantity:
Your information is safe with us.