N-Boc-PEG2-bromide
CAS No. : 165963-71-3
| Size | Price | Stock |
|---|---|---|
| 100mg | $14 | In-stock |
| 250mg | $19 | In-stock |
| 1g | $43 | In-stock |
| 5g | $151 | In-stock |
| 25g | $637 | In-stock |
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| 100 g | Get quote | |
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| Cat. No. : | HY-W006445 |
| M.Wt: | 312.20 |
| Formula: | C11H22BrNO4 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
N-Boc-PEG2-bromide is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG2-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
In Vitro: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
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