Mutant IDH1-IN-3


CAS No. : 1648909-73-2

1648909-73-2
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Cat. No. : HY-100476
M.Wt: 366.50
Formula: C22H30N4O
Purity: >98 %
Solubility:
Introduction of 1648909-73-2 :

Mutant IDH1-IN-3 (Compound 1) is a selective allosteric inhibitor of mutant isocitrate dehydrogenase 1 (IDH1). Mutant IDH1-IN-3 has an IC50 of 13 nM for R132H IDH1. Mutant IDH1-IN-3 inhibits the production of D-2-hydroxyglutaric acid (2HG) in cells. Mutant IDH1-IN-3 can be used in the study of cancer[1].

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