SX-682


CAS No. : 1648843-04-2

1648843-04-2
Price and Availability of CAS No. : 1648843-04-2
Size Price Stock
5mg $100 In-stock
10mg $150 In-stock
25mg $280 In-stock
50mg $460 In-stock
100mg $620 In-stock
200 mg Get quote
500 mg Get quote
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Cat. No. : HY-119339
M.Wt: 467.20
Formula: C19H14BF4N3O4S
Purity: >98 %
Solubility: DMSO : 200 mg/mL (ultrasonic)
Introduction of 1648843-04-2 :

SX-682 is an orally bioavailable, potent allosteric inhibitor of CXCR1 and CXCR2. SX-682 can block tumor myeloid-derived suppressor cells (MDSCs) recruitment and enhance T cell activation and antitumor immunity[1]. In Vivo:SX-682 (50 mg/kg; orally; twice a day on a Monday through Friday) has Meager to moderate effects as single agents on CRPC progression was observed, yet combination with ICB produced strong efficacy[2].

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