KC01
CAS No. : 1646795-59-6
| Size | Price | Stock |
|---|---|---|
| 1mg | $420 | In-stock |
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| 10 mg | Get quote | |
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| Cat. No. : | HY-120299 |
| M.Wt: | 365.55 |
| Formula: | C22H39NO3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
KC01 is an effective inhibitor of ABHD16A, with IC50s of 90 nM for hABHD16A and 520 nM for mABHD16A. KC01 significantly reduces lyso-PSs, and decreases lyso-PS and LPS-induced cytokine production in mouse macrophages [1].
IC50 & Target:90 nM for hABHD16A and 520 nM for mABHD16A[1]
In Vitro:KC01 (0-20 μM, 30 min) is a potent inhibitor of ABHD16A with an IC50 < 90 nM[1].
KC01 (1 μM, 4 h) significantly reduces lyso-PSs in colon cancer cells (COL205, K562, and MCF7)[1].
KC01 (1 μM, 4 h) reduces lyso-PS and LPS-induced cytokine production in mouse macrophages[1].
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