Aldicarb sulfoxide


CAS No. : 1646-87-3

1646-87-3
Price and Availability of CAS No. : 1646-87-3
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Cat. No. : HY-124104
M.Wt: 206.26
Formula: C7H14N2O3S
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 1646-87-3 :

Aldicarb sulfoxide is a metabolite of Aldicarb. Aldicarb sulfoxide affects the glutathione-linked enzymes in CHO-K1 cells. Aldicarb sulfoxide inhibits cholinesterase (ChE) and carboxylesterase (CaE) with IC50 of 10 μM for both in zebrafish[1][2]. IC50 & Target: IC50: 10 μM (zebrafish ChE); IC50: 10 μM (zebrafish CaE)[2] In Vitro: Aldicarb sulfoxide (10 μg/ml; 24 h) decreases the glutathione (GSH) concentration in CHO-K1 cells by 13.34%[1].
Aldicarb sulfoxide (10 μg/ml; 24 h) increases glutathione reductase (GR) activity in CHO-K1 cells by 101%[1].
Aldicarb sulfoxide (10 μg/ml; 24 h) increases glutathione peroxidase (GPx) activity increased in CHO-K1 cells by 32%[1].
Aldicarb sulfoxide (0.2-300 μM, 48 h) induces the increase of heart rate at low and decrease at higher concentration in zebrafish embryos[2].

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