DA-6886 (monohydrochloride)
CAS No. : 1645260-76-9
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|---|---|---|
| 1mg | $270 | Get quote |
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| 10mg | $971 | Get quote |
| 25mg | $1576 | Get quote |
| 50mg | $2197 | Get quote |
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| Cat. No. : | HY-19927A |
| M.Wt: | 443.37 |
| Formula: | C19H28Cl2N6O2 |
| Purity: | >98 % |
| Solubility: |
DA-6886 is a 5-Hydroxytryptamine receptor 4 (5-HT4) agonist. DA-6886 induces relaxation of the rat oesophagus preparation in a 5-HT4 receptor antagonist-sensitive manner. The evaluation of DA-6886 in CHO cells expressing hERG channels reveals that it inhibits hERG channel current with an pIC50 value of 4.3, indicating that the compound is 1000-fold more selective for the 5-HT4 receptor over hERG channels. DA-6886 can be used in the study of constipated irritable bowel syndrome[1][2].
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