YZ129


CAS No. : 1643120-60-8

1643120-60-8
Price and Availability of CAS No. : 1643120-60-8
Size Price Stock
5mg $60 In-stock
10mg $100 In-stock
25mg $220 In-stock
50mg $390 In-stock
100mg $650 In-stock
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Cat. No. : HY-114413
M.Wt: 300.31
Formula: C19H12N2O2
Purity: >98 %
Solubility: DMSO : 5.6 mg/mL (ultrasonic;warming;heat to 80°C)
Introduction of 1643120-60-8 :

YZ129 is an inhibitor of the HSP90-calcineurin-NFAT pathway against glioblastoma, directly binding to heat shock protein 90 (HSP90) with an IC50 of 820 nM on NFAT nuclear translocation. YZ129-induced GBM cell-cycle arrest at the G2/M phase promotes apoptosis and inhibited tumor cell proliferation and migration[1]. IC50 & Target: IC50: 820 nM (NFAT nuclear translocation)[1].

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