AMG8380
CAS No. : 1642112-32-0
Price and Availability of
CAS No. : 1642112-32-0
| Size | Price | Stock |
|---|---|---|
| 100 mg | Get quote | |
| 250 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-108425A |
| M.Wt: | 543.93 |
| Formula: | C25H16ClF2N3O5S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Introduction of
1642112-32-0
:
AMG8380, an orally active and less active enantiomer of AMG8379, can serves as a negative control. AMG8380 inhibits human and mouse voltage-gated sodium channel NaV1.7 with IC50s of 0.907 and 0.387 μM, respectively. AMG8380 blocks Tetrodotoxin (TTX)-sensitive native channels with an IC50 of 2560 nM[1].
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