Glycodeoxycholate (Sodium)


CAS No. : 16409-34-0

(Synonyms: Sodium glycyldeoxycholate)

16409-34-0
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Cat. No. : HY-N1427
M.Wt: 471.61
Formula: C26H42NNaO5
Purity: >98 %
Solubility: H2O : 100 mg/mL (ultrasonic);DMSO : 125 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 16409-34-0 :

Glycodeoxycholate Sodium (Sodium glycyldeoxycholate) is a bile salt. Glycodeoxycholate Sodium has cytotoxicity to cancer cell, changes the permeability of the pancreatic duct and decreases glucose levels[1][2][3]. In Vitro:Glycodeoxycholate Sodium (1-5 mM, 2h) has cytotoxicity to Caco-2 cells[1].
Glycodeoxycholate Sodium (1-15 mM, 1h) increases main pancreatic duct permeability and causes disruption of the tight junctions and the swelling of intercellular spaces between the duct cells[2]. In Vivo:Glycodeoxycholate Sodium (0.08 mg/kg, administered intranasally,single dose ) with sodium insulin decreases in glucose levels were 40% in sheep[1].

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