DYRKi


CAS No. : 1640364-04-0

1640364-04-0
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Cat. No. : HY-119607
M.Wt: 430.40
Formula: C20H13F3N4O2S
Purity: >98 %
Solubility:
Introduction of 1640364-04-0 :

DYRKi is an inhibitor of DYRK1 and DYRK1B with IC50 values of 3.7 µM and 90 nM, respectively, which is used as a potent antagonist of Hh/Gli signaling. DYRKi impairs SMO-dependent and SMO-independent oncogenic GLI activity in human medulloblastoma cells. DYRKi is promising for research of HH/GLI-associated cancers[1].

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