GS-9901


CAS No. : 1640247-87-5

1640247-87-5
Price and Availability of CAS No. : 1640247-87-5
Size Price Stock
5mg $250 In-stock
10mg $420 In-stock
25mg $900 In-stock
50mg $1215 In-stock
100mg $1640 In-stock
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Cat. No. : HY-100694
M.Wt: 477.88
Formula: C22H17ClFN9O
Purity: >98 %
Solubility: DMSO : ≥ 250 mg/mL
Introduction of 1640247-87-5 :

GS-9901 is a highly selective and orally active PI3Kδ inhibitor with an IC50 of 1 nM. GS-9901 has ≥100 fold selectivity for PI3Kα (IC50 of 750 nM), PI3Kβ (IC50 of 100 nM) and PI3Kγ (IC50 of 190 nM). GS-9901 can be used for the study of rheumatoid arthritis[1]. IC50 & Target:IC50: 1 nM (PI3Kδ)[1]. In Vivo:GS-9901 (0.3-3 mg/kg, orally, twice daily for 7 days) demonstrates efficacy in a rat model of arthritis[1].

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