TAPI-0
CAS No. : 163958-73-4
| Size | Price | Stock |
|---|---|---|
| 1mg | $270 | In-stock |
| 5mg | $770 | In-stock |
| 10mg | $1240 | In-stock |
| 50 mg | Get quote | |
| 100 mg | Get quote | |
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| Cat. No. : | HY-118694 |
| M.Wt: | 456.53 |
| Formula: | C24H32N4O5 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
TAPI-0 is a TACE (TNF-α converting enzyme; ADAM17) inhibitor with an IC50 of 100 nM. TAPI-0 is a MMP inhibitor and also attenuates TNF-α processing[1][2]. IC50 & Target:IC50: 100 nM (TACE)[2] In Vitro: TAPI-0 inhibits peptide deformylase (PDF) with an IC50 of 18 nM. TAPI-0 suppresses chlamydial growth by targeting the bacterial PDF[1].
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