Valbenazine (tosylate)


CAS No. : 1639208-54-0

(Synonyms: NBI-98854 (tosylate))

1639208-54-0
Price and Availability of CAS No. : 1639208-54-0
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5mg $135 In-stock
10mg $220 In-stock
25mg $420 In-stock
50mg $650 In-stock
100mg $950 In-stock
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Cat. No. : HY-16771A
M.Wt: 762.97
Formula: C38H54N2O10S2
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 1639208-54-0 :

Valbenazine tosylate (NBI-98854 tosylate) is a vesicular monoamine transporter 2 (VMAT2) inhibitor with the Ki of 110-190 nM[1]. In Vitro: Valbenazine exhibits VMAT2 binding affinity in rat striatum and human platelets with Kis of 110 and 150 nM, respectively[1]. In Vivo: Valbenazine (10 mg/kg; orally) induces ptosis (primarily an adrenergic response) and increases plasma prolactin primarily a dopaminergic response in rats[1].

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