JC124
CAS No. : 1638611-48-9
| Size | Price | Stock |
|---|---|---|
| 5mg | $180 | In-stock |
| 10mg | $290 | In-stock |
| 25mg | $480 | In-stock |
| 50mg | $680 | In-stock |
| 100mg | $925 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-120007 |
| M.Wt: | 382.86 |
| Formula: | C17H19ClN2O4S |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (ultrasonic;adjust pH to 3 with HCl) |
JC124 is a specific NLRP3 inflammasome inhibitor. JC124 has anti-inflammatory and neuroprotective effects[1]. In Vitro: JC124 shows selective inhibition of NLRP3 inflammasome formation and activation of caspase-1, and reduction of IL-1β both in vitro[1]. In Vivo: JC124 (100?mg/kg; i.p.; 4 doses; 30?min post-injury, 6, 24, and 30?h after TBI) treatment significantly decreases the number of injury-induced degenerating neurons, inflammatory cell response in the injured brain, and cortical lesion volume. JC124 also significantly reduces protein expression levels of NLRP3, ASC, IL-1 beta, TNFα, iNOS, and caspase-1[1].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- JC124
- Cat. No.:
- HY-120007
- Quantity:
Your information is safe with us.