HIV-1 integrase inhibitor 4
CAS No. : 1638504-66-1
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| Cat. No. : | HY-108820 |
| M.Wt: | 514.50 |
| Formula: | C24H20F2N4O5S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
HIV-1 integrase inhibitor 4 is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 3.7 nM. IC50 & Target: IC50: 3.7 nM (INST)[1] In Vitro: HIV-1 integrase inhibitor 4 (compound 4f) is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 3.7 nM. HIV-1 integrase inhibitor 4 shows potent activity against recombinant HIV IN in biochemical assays and good efficacy in assays done in cell culture against a broad panel of viral mutants carrying the major RAL and DTG IN resistance mutations[1].
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