TAPI-1
CAS No. : 163847-77-6
| Size | Price | Stock |
|---|---|---|
| 1mg | $238 | In-stock |
| 5mg | $871 | In-stock |
| 10mg | $1558 | In-stock |
| 50 mg | Get quote | |
| 100 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-16657 |
| M.Wt: | 499.60 |
| Formula: | C26H37N5O5 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 31 mg/mL |
TAPI-1 is a TACE (ADAM17) inhibitor and blocks the shedding of several cell surface proteins[1]. TAPI-1 is also a metalloproteinase (MMP) inhibitor[2].
IC50 & Target: TACE (ADAM17)[1], MMP[2]
In Vitro: TAPI-1 (1 µM for 30 min) increases cell viability in LPS-treated HK-2 cells[1].
TAPI-1 attenuates oxidative stress and inflammatory cytokines[1]
LPS treatment significantly induces renal IL-6 and TNFα mRNA expression, while these changes is attenuated with TAPI-1 pretreatment in LPS-treated HK-2 cells[1].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- TAPI-1
- Cat. No.:
- HY-16657
- Quantity:
Your information is safe with us.