p38 MAP Kinase Inhibitor IV


CAS No. : 1638-41-1

1638-41-1
Price and Availability of CAS No. : 1638-41-1
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Cat. No. : HY-112401
M.Wt: 456.94
Formula: C12H4Cl6O4S
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 1638-41-1 :

p38 MAP Kinase Inhibitor IV is a highly specific ATP-competitive p38α MAPK inhibitor with IC50s of 0.13 and 0.55 μM for p38α and p38β MAPK, respectively[1]. In Vitro: p38 MAP Kinase Inhibitor IV (MT4) shows IC50 values of 0.13, 0.55, 5.47, and 8.63μM for p38α, β, χ, andδ, respectively. p38 MAP Kinase Inhibitor IV has the suppressive action on the release of TNF-alpha and IL-1beta in PBMC with IC50 values of 22 and 44 nM, respectively[1].

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