AF64394


CAS No. : 1637300-25-4

1637300-25-4
Price and Availability of CAS No. : 1637300-25-4
Size Price Stock
5mg $92 In-stock
10mg $138 In-stock
25mg $250 In-stock
50mg $375 In-stock
100mg $562 In-stock
200 mg Get quote
500 mg Get quote
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Cat. No. : HY-12664
M.Wt: 393.87
Formula: C21H20ClN5O
Purity: >98 %
Solubility: DMSO : ≥ 125 mg/mL
Introduction of 1637300-25-4 :

AF64394 is a GPR3 inverse agonist, with a pIC50 of 7.3. IC50 & Target: pIC50: 7.3 (GPR3)[1]. In Vitro: AF64394 is a GPR3 inverse agonist, with a pIC50 of 7.3. AF34394 and related compounds are only of modest potency and are relatively lipophilic (e.g., AF34394 clogP=5.2, LLE=2.1, and 14b clog P=3.1 and LLE=3.2) the series shows promising SAR and represents an excellent start point for further optimization[1].

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