Mavoglurant (racemate)
CAS No. : 1636881-61-2
(Synonyms: AFQ-056 (racemate))
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| 5mg | $840 | In-stock |
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| Cat. No. : | HY-15257A |
| M.Wt: | 313.39 |
| Formula: | C19H23NO3 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
Mavoglurant racemate (AFQ-056 racemate) is the racemate of Mavoglurant. Mavoglurant is a novel, non-competitive mGlu5 receptor antagonist[1]. Mavoglurant (racemate) is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. In Vitro: For antagonistic activity, ( )-mavoglurant, the ( )-enantiomer shows IC50 of 0.11 μM and 0.03 μM (Ca2+ and PI-turnover) whereas the (+)-enantiomer ((+)-10) shows only 37% and 18% inhibition at 10 μM[1].
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