(R)-MDL-101146
CAS No. : 163660-53-5
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| Cat. No. : | HY-120039 |
| M.Wt: | 632.62 |
| Formula: | C29H37F5N4O6 |
| Purity: | >98 % |
| Solubility: |
(R)-MDL-101146 is the R-isomer of MDL-101146. MDL-101146 is an orally active, competitive and reversible inhibitor against human neutrophil elastase (HNE) with a Ki value of 25 nM. MDL-101146 inhibits HNE-induced hemorrhage in hamsters. MDL-101146 is promising for research of emphysema, rheumatoid arthritis, chronic bronchitis, cystic fibrosis, adult respiratory distress syndrome and glomerulonephritis[1].
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