PNR-7-02
CAS No. : 1633660-76-0
| Size | Price | Stock |
|---|---|---|
| 5mg | $360 | In-stock |
| 10mg | $575 | In-stock |
| 25mg | $1150 | In-stock |
| 50mg | $1840 | In-stock |
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| 200 mg | Get quote | |
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| Cat. No. : | HY-117664 |
| M.Wt: | 445.92 |
| Formula: | C24H16ClN3O2S |
| Purity: | >98 % |
| Solubility: |
PNR-7-02 inhibits Pol η function with an IC50 value of near 8 μM, which binds to the little finger domain. PNR-7-02 is also an inhibitor against hRev1 and hpol lambda (λ). PNR-7-02 acts synergistically with Cisplatin (HY-17394) to kill chronic myeloid leukaemia and ovarian cancer cell lines. PNR-7-02 is an indole thio-barbituric acid (ITBA) derivative with both N-napthoyl moiety and 5-chloro substituent on the indole ring[1][2].
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