Cannabisin F
CAS No. : 163136-19-4
| Size | Price | Stock |
|---|---|---|
| 1mg | $480 | In-stock |
| 5mg | $1200 | Get quote |
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| 50 mg | Get quote | |
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| Cat. No. : | HY-N3532 |
| M.Wt: | 624.68 |
| Formula: | C36H36N2O8 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Cannabisin F is a SIRT1 modulator. Cannabisin F, as a hempseed lignanamide, can be used for the research of anti-inflammatory and anti-oxidative. Cannabisin F may be a potential agent of neurodegenerative diseases as modulators of SIRT1/NF-κB and Nrf2[1].
IC50 & Target: SIRT1[1]
In Vitro: Cannabisin F (0~15 μM; 1 hour; BV2 microglia cells) inhibits the phosphorylation of IκBα, p65, but enhances the expression of Nrf2 and HO-1[1].
Cannabisin F (0~15 μM; 24 hours; BV2 microglia cells) has no significant effect on cell survival, inhibits IL-6 and TNF-α production and their mRNA expression, inhibits the production of ROS and increases the expression of SIRT1[1].
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