CDK8-IN-1


CAS No. : 1629633-48-2

1629633-48-2
Price and Availability of CAS No. : 1629633-48-2
Size Price Stock
5mg $280 In-stock
10mg $400 In-stock
25mg $670 In-stock
50mg $900 In-stock
100mg $1200 In-stock
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Cat. No. : HY-103492
M.Wt: 255.20
Formula: C11H8F3N3O
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 1629633-48-2 :

CDK8-IN-1 is a potent and selective CDK8 inhibitor with an IC50 of 3 nM. IC50 & Target: IC50: 3 nM (CDK8)[1]. In Vivo: CDK8-IN-1 displays low systemic clearance, very good exposure and oral bioavailability. The tmax is 0.25 h by PO. The mean values of Cmax are 9940 μg/L, 12740 μg/L by IV and PO respectively. The values of AUC are 9378, 25952 by IV and PO respectively[1].

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