| Size | Price | Stock |
|---|---|---|
| 5mg | $280 | In-stock |
| 10mg | $400 | In-stock |
| 25mg | $670 | In-stock |
| 50mg | $900 | In-stock |
| 100mg | $1200 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
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Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-103492 |
| M.Wt: | 255.20 |
| Formula: | C11H8F3N3O |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
CDK8-IN-1 is a potent and selective CDK8 inhibitor with an IC50 of 3 nM. IC50 & Target: IC50: 3 nM (CDK8)[1]. In Vivo: CDK8-IN-1 displays low systemic clearance, very good exposure and oral bioavailability. The tmax is 0.25 h by PO. The mean values of Cmax are 9940 μg/L, 12740 μg/L by IV and PO respectively. The values of AUC are 9378, 25952 by IV and PO respectively[1].
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