GMA-839
CAS No. : 162882-76-0
(Synonyms: WAY 141839; Co 2-6749)
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| Cat. No. : | HY-117955 |
| M.Wt: | 388.46 |
| Formula: | C21H31F3O3 |
| Purity: | >98 % |
| Solubility: |
GMA-839 is a selective modulator of the γ-aminobutyric acid A receptor (GABAA) with an IC50 value of 230 nM. GMA-839 exhibits potent anxiolytic-like activity, demonstrating significant dose-dependent anxiolytic effects in animal models, with an effective oral dose of 1.6 mg/kg. Significant increases in punished responding were observed in squirrel monkeys and pigeons. GMA-839 shows promise for research in the field of anxiolytics[1].
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