N-Isovaleroylglycine (Standard)
CAS No. : 16284-60-9
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| Cat. No. : | HY-W015464R |
| M.Wt: | 159.18 |
| Formula: | C7H13NO3 |
| Purity: | >98 % |
| Solubility: |
N-Isovaleroylglycine (Standard) is the analytical standard of N-Isovaleroylglycine (HY-W015464). This product is intended for research and analytical applications. N-Isovaleroylglycine is a peptidylglycine α-amidating monooxygenase (PAM) inhibitor with a Ki value of 2.0 mM against human hsPAM. N-Isovaleroylglycine undergoes oxidative cleavage by purified rat PAM to produce fatty acid amide and glyoxylic acid. N-Isovaleroylglycine exerts competitive inhibition by binding to hsPAM, blocking the amidation of dansyl-Tyr-Val-Gly. N-Isovaleroylglycine exhibits lowered urinary abundance in MRSA-infected mice, which qualifies it as a non-invasive biomarker. N-Isovaleroylglycine can be used in studies related to Staphylococcus aureus pneumonia and diabetic foot[1][2][3].
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