HQL-79
CAS No. : 162641-16-9
| Size | Price | Stock |
|---|---|---|
| 5mg | $80 | In-stock |
| 10mg | $140 | In-stock |
| 25mg | $317 | In-stock |
| 50mg | $540 | In-stock |
| 100mg | $864 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-108259 |
| M.Wt: | 377.48 |
| Formula: | C22H27N5O |
| Purity: | >98 % |
| Solubility: | DMSO : 2 mg/mL (ultrasonic;warming;heat to 60°C) |
HQL-79, a potent, selective and orally active human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor, highly selectively inhibits the synthesis of PGD2, and acts as an anti-allergic agent, with a Kd of 0.8 μM and an IC50 of 6 μM. Shows no obvious effect on COX-1, COX-2, m-PGES, or L-PGDS[1].
IC50 & Target: IC50: 6 μM (H-PGDS)[1]
Kd: 0.8 μM (H-PGDS)[1]
In Vitro: HQL-79 is a competitive inhibitor against substrate PGH2 and a non-competitive one against GSH[1].
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