Radioprotectin-1
CAS No. : 1622006-09-0
| Size | Price | Stock |
|---|---|---|
| 5mg | $370 | In-stock |
| 10mg | $550 | In-stock |
| 50mg | $1250 | In-stock |
| 100mg | $1650 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-114380 |
| M.Wt: | 486.92 |
| Formula: | C23H19ClN2O6S |
| Purity: | >98 % |
| Solubility: | H2O : ≥ mg/mL;DMSO : 125 mg/mL (ultrasonic) |
Radioprotectin-1 is a potent and specific nonlipid agonist of lysophosphatidic acid receptor 2 (LPA2), with an EC50 value of 25 nM for murine LPA2 subtype[1].
IC50 & Target: EC50: 25 nM (murine LPA2 subtype)[1]
In Vitro: Radioprotectin-1 is a potent agonist of LPA2 with an EC50 of 5 pM and functions as a full agonist at the human ortholog of LPA2[1].
Radioprotectin-1 (0-3 μM; 15 minutes) effectively reduces apoptosis induced by γ-irradiation and the radiomimetic drug Adriamycin in cells that expressed LPA2 either endogenously or after transfection[1].
In Vivo: Radioprotectin-1 is a high-potency specific agonist of the murine LPA2 GPCR [1].
Radioprotectin-1 (0.1 mg/kg, 0.3 mg/kg; s.c.; every 12 hours; for 3 days) decreases the mortality of C57BL/6 mice in models of the hematopoietic acute radiation syndromes (HE-ARS) and gastrointestinal acute radiation syndromes (GI-ARS) [1].
Radioprotectin-1 exerts its radioprotective and radiomitigative action through specific activation of the upregulated LPA2 GPCR in Lgr5+stem cells[1].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- Radioprotectin-1
- Cat. No.:
- HY-114380
- Quantity:
Your information is safe with us.