Tigolaner
CAS No. : 1621436-41-6
(Synonyms: BAY-1272858)
Price and Availability of
CAS No. : 1621436-41-6
| Size | Price | Stock |
|---|---|---|
| 5mg | $250 | In-stock |
| 10mg | $400 | In-stock |
| 25mg | $760 | In-stock |
| 50mg | $1220 | In-stock |
| 100mg | $1950 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-109077 |
| M.Wt: | 552.81 |
| Formula: | C21H13ClF8N6O |
| Purity: | >98 % |
| Solubility: | DMSO : 25 mg/mL (ultrasonic) |
Introduction of
1621436-41-6
:
Tigolaner (BAY-1272858) acts on γ-aminobutyric acid (GABA) and glutamate-gated chloride channels. Tigolaner has antiparasitic activity[1].
In Vivo:Tigolaner (intravenous injection/topical administration; 1.5 mg/kg / 14.5 mg/kg; single dose) exerts anti-flea and anti-tick effects in cats[1].
Plasma Pharmacokinetic Analysis in cats[1]
| Route | Dose rate mg/kg | T1/2 (h) | Tmax (h) | Cmax (μg/L) | AUClast (mg·h/L) | AUCinf (mg·h/L) | CL-pred (L/h/kg) | Vz-pred (L/kg) |
| topical | 14.5 | 568.2 | 297.0 | 1245.1 | 1516 | 1566 | / | / |
| i.v. | 1.5 | 515.4 | / | / | 298 | 300.1 | 0.005 | 4.00 |