PF-06658607


CAS No. : 1621002-24-1

1621002-24-1
Price and Availability of CAS No. : 1621002-24-1
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5mg $175 In-stock
10mg $280 In-stock
25mg $520 In-stock
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Cat. No. : HY-12679
M.Wt: 464.52
Formula: C27H24N6O2
Purity: >98 %
Solubility:
Introduction of 1621002-24-1 :

PF-06658607 is an alkynylated irreversible Brutons tyrosine kinase (BTK) inhibitor that covalently reacts with active site cysteines in the ATP-binding pocket. PF-06658607 can be used to detect "off "-targets for covalent kinase inhibitors in cancer cells. The alkyne moiety allows for azide-based detection probe via copper-catalyzed click chemistry[1].

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