SB-215505
CAS No. : 162100-15-4
| Size | Price | Stock |
|---|---|---|
| 5mg | $440 | In-stock |
| 10mg | $615 | In-stock |
| 25mg | $985 | In-stock |
| 50mg | $1380 | In-stock |
| 100mg | $1865 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-18596 |
| M.Wt: | 337.80 |
| Formula: | C19H16ClN3O |
| Purity: | >98 % |
| Solubility: | DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C) |
SB-215505 is an orally active and subtype-selective 5-HT2B receptor antagonist with pKi values of 8.3, 6.77, 7.66 for 5-HT2B, 5-HT2A, 5-HT2C, respectively[1]. SB-215505 increases wakefulness and motor activity in rats[2]. In Vitro:SB-215505 is 30 fold selective for the 5-HT2B over the 5-HT2A receptor, and only marginally selective over the 5-HT2C receptor[1]. In Vivo:SB-215505 (0.1-1.0 mg/kg; i.p.; two doses) dose-dependently increases wakefulness (W) and decreases IS, PS, SWS-2 in rats[2].
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