Boc-piperazine-benzoic acid


CAS No. : 162046-66-4

162046-66-4
Price and Availability of CAS No. : 162046-66-4
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Cat. No. : HY-W013249
M.Wt: 306.36
Formula: C16H22N2O4
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 162046-66-4 :

Boc-piperazine-benzoic acid is a PROTAC linker and can be used in the synthesis of PROTACs, such as PROTAC androgen receptor (AR) degrader ARD-2128 (HY-13229)[1]. In Vitro: ARD-2128 is a highly potent, orally bioavailable PROTAC androgen receptor (AR) degrader. ARD-2128 effectively reduces AR protein, suppresses AR-regulated genes in tumor tissues, and inhibits growth of tumor without signs of toxicity. ARD-2128 has the potential for the research of the prostate cancer[1].

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