Cimlanod
CAS No. : 1620330-72-4
(Synonyms: BMS-986231; CXL-1427)
| Size | Price | Stock |
|---|---|---|
| 5mg | $164 | In-stock |
| 10mg | $255 | In-stock |
| 50mg | $645 | In-stock |
| 100mg | $950 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-118643 |
| M.Wt: | 177.18 |
| Formula: | C5H7NO4S |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic) |
Cimlanod (BMS-986231) is a second-generation Nitroxyl (HNO) donor for heart failure. Cimlanod (BMS-986231) delivers HNO via pH-dependent chemical breakdown when exposed to the neutral pH environment of the bloodstream. Cimlanod (BMS-986231) possesses positive lusitropic and inotropic as well as vasodilatory effects. Cimlanod is the prodrug of CXL-1020 (HY-147384)[1][2]. In Vivo:Cimlanod (50 mg/kg/min, iv for 3 hours) exhibits positive inotropic effects, improved diastolic function, and moderate vasodilation, reduces myocardial oxygen consumption in canine heart failure models[3].
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