Autotaxin-IN-1
CAS No. : 1619971-30-0
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| Cat. No. : | HY-123637 |
| M.Wt: | 405.45 |
| Formula: | C21H23N7O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Autotaxin-IN-1 is a potent autotaxin inhibitor, which has favorable potency (IC50=2.2 nM), PK properties, and a robust PK/PD relationship. Autotaxin-IN-1 is used in treatment of osteoarthritis pain[1].
IC50 & Target: IC50: 2.2 nM (Autotaxin)[1]
In Vivo: Autotaxin-IN-1 (i.v.; 1.0mg/kg) has T1/2 of 1.14 hours[1].
Autotaxin-IN-1 (p.o.; 10 mg/kg) has Cmax of 660 nM and AUC of 3440 nM?h[1].
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- Autotaxin-IN-1
- Cat. No.:
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