YM-358 hydrate (potassium)


CAS No. : 161800-08-4

161800-08-4
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Cat. No. : HY-105011A
M.Wt: 455.58
Formula: C22H24KN8O
Purity: >98 %
Solubility:
Introduction of 161800-08-4 :

YM-358 hydrate (potassium) is an orally active angiotensin II type 1 (AT1)-receptor antagonist. YM-358 hydrate (potassium) can decrease cardiac volume overload. YM-358 hydrate (potassium) can be used for the research of cardiovascular disease, such as hypertension[1]. In Vivo:YM-358 hydrate (potassium) (30 mg/kg, p.o., daily for 2-4 weeks) attenuates increases of left ventricle (LV)/body weight (BW), left atrium (LA)/BW, right ventricle (RV)/BW and heart/BW ratiosin abdominal aortocaval shunt rats[1].

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