Rasagiline (mesylate)
CAS No. : 161735-79-1
(Synonyms: (R)-AGN1135 (mesylate); TVP1012 (mesylate))
| Size | Price | Stock |
|---|---|---|
| 1g | $41 | In-stock |
| 5g | $159 | In-stock |
| 25g | $546 | In-stock |
| 100g | $1786 | In-stock |
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| Cat. No. : | HY-14605 |
| M.Wt: | 267.34 |
| Formula: | C13H17NO3S |
| Purity: | >98 % |
| Solubility: | H2O : 25 mg/mL (ultrasonic) |
Rasagiline (R-AGN1135) mesylate is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor with IC50s of 4.43 nM and 412 nM for rat brain MAO B and A activity, respectively[1]. Rasagiline (mesylate) is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. IC50 & Target: IC50: 4.43 nM (rat brain MAO B), 412 nM (rat brain MAO A)[1] In Vitro: Rasagiline (0.25 nM; 96 hours) significantly increases the proliferation rates of SH-SY5Y and 1242-MG upon Dexamethasone (10 μM) treatment[2]. In Vivo: Rasagiline is neuroprotective in a transgenic model of multiple system atrophy. Motor behavioural tests show improvements in motor deficits associated with 2.5 mg/kg Rasagiline therapy[3].
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