Tebipenem
CAS No. : 161715-21-5
(Synonyms: LJC 11036)
| Size | Price | Stock |
|---|---|---|
| 5mg | $50 | In-stock |
| 10mg | $80 | In-stock |
| 25mg | $160 | In-stock |
| 50mg | $256 | In-stock |
| 100mg | $400 | In-stock |
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| Cat. No. : | HY-A0076 |
| M.Wt: | 383.49 |
| Formula: | C16H21N3O4S2 |
| Purity: | >98 % |
| Solubility: | DMSO : 33.33 mg/mL (ultrasonic);H2O : 7.14 mg/mL (ultrasonic) |
Tebipenem is an orally available carbapenem antibiotic, shows broad-spectrum activity against Gram-positive and -negative bacteria, except for Pseudomonas aeruginosa. In Vitro: Tebipenem exhibits slow tight-binding inhibition at low micromolar concentrations versus the chromogenic substrate nitrocefin, and apparent Km and kcat values of 0.8 μM and 0.03 min-1, respectively[1]. Tebipenem shows potent activity against B. pseudomallei, with MIC50 and MIC90 values of both 2 mg/L[2]. Tebipenem shows good activity against S. pneumoniae, with the MIC range of ≤0.25 μg/mL in all of the S. pneumoniae isolates[3].
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